CTSB cis protein quantitative trait locus polygenic score

Biomarker

1 paper1 finding

  • Humans1

Associations

1

Cognitive function

upin humans1

1 study
  1. CTSB cis protein quantitative trait locus polygenic score predicts cognitive function in humans (β=0.031 (95% CI, 0.009-0.054)).

    “a cis protein quantitative trait locus polygenic score (β=0.031 [95% CI, 0.009-0.054]; n=8884) predicted better cognitive performance.”

    Humansn = 8,884

    Blood protein linked to lower brain lesion volume

    Stroke16 Oct 2026

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 11 in 12 months
Stroke

Blood protein linked to lower brain lesion volume

Higher blood levels of the protein cathepsin B were linked to lower lesion volume, with an association estimate of minus 0.09 in 5,260 people.Higher blood levels of the protein cathepsin B were linked to lower lesion volume, with an association estimate of minus 0.09 in 5,260 people.

Cohort study of 5,260 UK Biobank participantsMechanisms

Limit: The postmortem comparison supporting lesion-related cathepsin B changes involved only eight samples