CpG-site-specific DNA methylation

Biomarker

1 paper studies it1 finding

  • Human trial1

Interventions

1

Caloric restriction

no changein humans1

1 study
  1. Caloric restriction has no effect on CpG-site-specific DNA methylation in humans.

    “No CpG-site-specific changes with CR reached epigenome-wide significance (FDR<0.05).”

    Human trialhealthy, non-obese adults; compared with ad libitum dietwhole blood12% average calorie restriction12 and 24 monthsn = 197

    Epigenome-wide association study analysis of calorie restriction in humans, CALERIE™ Trial analysis

    bioRxiv (Cold Spring Harbor Laboratory)Preprint

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