Cognitive testing

Biomarker

5 papers

  • Human trial1
  • Humans4

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Scientific Reports

A protein mutation curbs brain damage in mice with dementia

Young and 18-month-old mice with an altered UCHL1 protein showed less white matter injury and better sensorimotor and cognitive performance in a dementia model.Young and 18-month-old mice with an altered UCHL1 protein showed less white matter injury and better sensorimotor and cognitive performance in a dementia model.

Experiments in miceMechanisms
Imaging Neuroscience

Brain diffusion scans predict dementia risk and mental decline

Among 5,230 adults aged 45 and older followed for a median 9.8 years, one brain diffusion marker best predicted cognitive decline, while two best predicted dementia risk.Among 5,230 adults aged 45 and older followed for a median 9.8 years, one brain diffusion marker best predicted cognitive decline, while two best predicted dementia risk.

Cohort study of 5,230 peopleDementia
JMIR Aging

AI detects cognitive concerns in older adults with normal tests

In an observational study, 13.8% of older adults with normal cognitive test scores had memory or thinking concerns documented in their health records.In an observational study, 13.8% of older adults with normal cognitive test scores had memory or thinking concerns documented in their health records.

Cohort study of 15,750 peopleBiomarkers
PLOS One

Oral bacteria linked to cognition in UK and Belgian adults

Across 60 healthy younger and older adults in the UK and Belgium, researchers found shared bacterial associations with cognitive performance despite geographic microbiome…Across 60 healthy younger and older adults in the UK and Belgium, researchers found shared bacterial associations with cognitive performance despite geographic microbiome differences.

Cohort study of 60 peoplePopulations