Reproductive Toxicology·Aug 16All-trans Retinoic Acid regulates cellular senescence of mouse embryonic palatal mesenchyme (MEPM) cells in developing cleft palatesExperiments in miceCell cycle regulationPaper
Biogerontology·Aug 13Cytoskeleton-associated protein 4: a double-edged sword in cell growth and agingReviewMechanismsPaper
Nutrients·Jul 30Vitamin D's Impact on Cancer Incidence and Mortality: A Systematic ReviewSystematic review of studies in peopleVitamin DPaper
Current Issues in Molecular Biology·Jul 29Angiotensin II and Cardiovascular Disease: Balancing Pathogenic and Protective PathwaysReviewRenin–angiotensin systemPaper
bioRxiv·Jul 16Downregulation of LATS1/2 Drives Endothelial Senescence-Associated Stemness (SAS) and Atherothrombotic Lesion FormationPreprint: study in peopleCellular senescencePaper
Epigenomics·Jul 7Methylation levels in keratinocyte basal cells reflect donor age and associate with altered cellular proliferation pathwaysStudy of 9 peopleDNA methylationPaper
Mechanisms of Ageing and Development·Jul 1Galectin-3-binding protein is a risk factor for diabetes, metabolic syndrome, and inflammation. Cross-sectional and longitudinal results from the InCHIANTI studyCohort study of 866 peopleMetabolic syndromePaper
bioRxiv·Jun 26Microgravity Accelerates Skeletal Muscle Degeneration: Functional and Transcriptomic Insights from a Muscle Lab-on-Chip Model Onboard the ISSPreprint: experiments in human cellsOxidative phosphorylationPaper
Ageing Research Reviews·Jun 17The role of microRNAs in the pathophysiology of the aging eyeReviewEyePaper
bioRxiv·Jun 4The broccoli derivative sulforaphane extends lifespan by slowing the transcriptional aging clockPreprint: experiments in wormsInterventionsPaper
Journal for Immunotherapy of Cancer·May 28Dual roles of IRE1α inhibition in reversing mitochondrial ROS-induced CD8⁺ T-cell senescence and exerting direct antitumor effects in multiple myelomaExperiments in miceOxidative stress and ROS signalingPaper
International Journal of Molecular Sciences·May 14CCN2 Activates Cellular Senescence Leading to Kidney Fibrosis in Folic Acid-Induced Experimental NephropathyExperiments in miceCellular senescencePaper
Cytoskeleton·Apr 10Conserved Phosphorylation of the Myosin1e TH1 Domain Impacts Membrane Association and Function in Yeast and WormsExperiments in wormsPlasma membranePaper
bioRxiv·Apr 8Bisphosphonates Trigger Anti-Ageing Effects Across Multiple Cell Types and Protect Against SenescencePreprint: non-randomized trial in peopleBisphosphonatesPaper
Endocrinology·Apr 3Weight Gain With Advancing Age Is Controlled by the Muscarinic Acetylcholine Receptor M4 in Male MiceExperiments in miceMechanismsPaper
The Journal of Clinical Investigation·Apr 3ATM-dependent DNA damage response constrains cell growth and drives clonal hematopoiesis in telomere biology disordersCohort study of 166 peopleTelomerase and telomere maintenancePaper
Scientific Reports·Mar 20Comprehensive analysis of senescence-related genes identifies prognostic clusters with distinct characteristics in gliomaComputational studyBiomarkersPaper
FASEB Journal·Mar 18Ovarian aging-associated downregulation of GPX4 expression regulates ovarian follicular development by affecting granulosa cell functions and oocyte qualityStudy in peopleGPX4Paper
Nature Metabolism·Mar 16The cyclic metabolic switching theory of intermittent fastingReviewIntermittent fastingPaper
Bioresource Technology·Mar 5Metabolic reprogramming and machine learning-guided cofactor engineering to boost nicotinamide mononucleotide production in Escherichia coliExperiments in bacteriaInterventionsPaper
Journal of Applied Biomedicine·Mar 4Syringin protects high glucose-induced BMSC injury, cell senescence, and osteoporosis by inhibiting JAK2/STAT3 signalingExperiments in mouse cellsBones and jointsPaper
Life Sciences·Feb 27GLDC alleviates cisplatin-induced apoptosis, cellular senescence, and production of reactive oxygen species via regulating UCP1 in the kidneyExperiments in miceCell cycle regulationPaper
Trends in Cell Biology·Jan 23Splice age: mTORC1-mediated RNA splicing in metabolism and ageingReviewRNA splicingPaper
Maturitas·Jan 23Optimizing the regenerative potential of vaginal fibroblasts: The role of autologous platelet-rich plasma and hyaluronic acid in vitroExperiments in human cellsHyaluronic acidPaper
Nature Communications·Jan 22OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced senescence in human fibroblastsExperiments in human cellsTelomerase and telomere maintenancePaper
Oral Diseases·Jan 21LIMA1 Is a Prognostic Senescence-Inhibitory Gene in Head and Neck Squamous CarcinomaStudy in peopleCellular senescencePaper
Current Medicinal Chemistry·Jan 8Interaction between microRNA and KRAS in GlioblastomaReviewMechanismsPaper
GSA 2024 Abstract·Jan 1HOW OXIDATIVE DAMAGE TO TELOMERES PROMOTES PREMATURE CELLULAR SENESCENCEExperiments in human cellsTelomerase and telomere maintenancePaper
Experimental Neurology·Dec 30Investigating the effect of metformin on chemobrain: Reports from cells to bedsideReviewMetforminPaper