Cdc42

1 paper

Animals1

Latest

7 in 12 months

Molecular Neurobiology11 Oct

Integrative Transcriptomic and Interactome Analyses Prioritize Candidate Genes for Alzheimer's Disease

Computational studyMechanisms

Journal of Oral Biosciences3 Oct

Shared structural alterations, divergent functional responses in salivary and lacrimal glands: A conceptual framework from Cdc42-mediated polarity disruption

ReviewMechanisms

bioRxiv14 Aug

Targeting CDC42 with CASIN Reprograms Cell-Type-Specific Transcriptomes and MAPK-Driven Transcription Factor Networks in the Aging Brain

Preprint: experiments in miceMAPK/ERK signalling

Annals of Neurosciences9 Mar

A Meta-analysis to Identify Common Key Genes Across Ageing, Alzheimer's and Parkinson's Diseases

Computational studyMechanisms

PLOS Biology12 Feb

Cdc42 interacts with chaperone Ydj1 to enhance its stability and partitioning during asymmetric cell division and aging in yeast

Experiments in yeastProtein folding and chaperones

Aging Cell8 Feb

Overactivation of Cdc42 GTPase Impairs the Cytotoxic Function of NK Cells From Old Individuals Towards Senescent Fibroblasts

Experiments in human cellsCell killing (cytotoxicity)

Human Molecular Genetics7 Jan

Integrated analysis of spatial and single-cell profiles reveals cell type-specific regulation of synaptic plasticity in human brain aging

Computational studySynapse

iScience2 Sep

Control of stress-activated Cdc42 dynamics by the MAP kinase Sty1-NDR kinase Orb6 regulatory axis

Experiments in yeastMechanisms

bioRxiv30 Aug

Molecular aging is the main driver of Parkinson’s Disease

Preprint: experiments in miceParkinson's disease

Nature Aging27 Aug

Mevalonate metabolites boost aged oocyte quality through prenylation of small GTPases

Experiments in animalsInterventions