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CD8+ T-lymphocyte infiltration

Biomarker

1 paper1 finding

  • Humans1

Upstream

1

Cellular senescence

upin human cells1

1 study

  1. Cellular senescence increases CD8+ T-lymphocyte infiltration in human cells.

    “Meanwhile, KDM4A-driven senescence suppressed tumor growth and enhanced intratumoral CD8+ T-lymphocyte infiltration via enhancing SASP-associated secretion.”

    Cellsvia enhancing SASP-associated secretioncolorectal cancer

    KDM4A-induced tumor senescence enhances the efficacy of immunotherapy by inhibiting AGT-PHB1 axis-mediated mitophagy in colorectal cancer

    Autophagy9 Sep 2025

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