CD47+ reticulated platelets

1. BPIFB4 is associated with CD47+ reticulated platelets in humans.

   “centenarians displayed an elevated percentage of circulating CD47+ reticulated platelets (RPs), a condition mimicked by LAV-BPIFB4 carriers”

   Humansin centenarians and LAV-BPIFB4 carriers

   The LAV-BPIFB4-Platelet-CD47 Axis: A Novel Mechanism Associated With Immune Resilience in Longevity

   Aging cell·25 Jun 2026

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