Cardiovascular risk composite

Biomarker

1 paper2 findings

  • Humans1

Effects

1

Cognitive function

no changein humans1

1 study
  1. Cardiovascular risk composite has no effect on cognitive function in humans.

    “There was not a significant correlation between the cardiovascular composite and the resilience scores.”

    HumansDown syndromen = 262

    Cardiovascular Risk Composite and Time of Amyloid Accumulation and Cognitive Decline in Down Syndrome Alzheimer's Disease

    AAIC 2025 abstract24 Dec 2025

Associations

1

Amyloid-beta accumulation

upin humans1

1 study
  1. Cardiovascular risk composite is associated with amyloid-beta accumulation in humans (r = .156, p = .016).

    “there was a significant positive association between the cardiovascular composite ( r = .156, p = .016) and resistance score; higher cardiovascular composite was associated with greater than expected Aβ for age”

    HumansDown syndromebrainn = 262

    Cardiovascular Risk Composite and Time of Amyloid Accumulation and Cognitive Decline in Down Syndrome Alzheimer's Disease

    AAIC 2025 abstract24 Dec 2025

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