Calretinin-immunoreactive neuron density

Older age has no effect on calretinin-immunoreactive neuron density in humans (AC: younger 1.2 ± 0.3 × 10−3 versus older 0.9 ± 0.2 × 10−3 per mm2 plexus; DC: 1.4 ± 0.2 × 10−3 versus 1.3 ± 0.3 × 10−3 per mm2 plexus).

“For the myenteric plexus (MP) of both age groups, the densities of calretinin-IR neurons were similar”

HumansMacroscopically normal tissue from patients undergoing lower bowel cancer resectionmyenteric plexus of ascending and descending colon

Age-Related Loss of GPR68 and Calretinin Immunoreactive Neurons Within the Mucosa, Not the Myenteric Plexus of Human Colon

British journal of biomedical science·7 Apr 2026

Older age is associated with calretinin-immunoreactive neuron density in humans (AC: younger 9.8 ± 0.5 versus older 3.2 ± 0.1/pixel; DC: younger 11.5 ± 0.9 versus older 7.4 ± 0.3/pixel).

“but reduced in the mucosa of older adults for both AC”

HumansMacroscopically normal tissue from patients undergoing lower bowel cancer resectionmucosa of ascending and descending colon

Age-Related Loss of GPR68 and Calretinin Immunoreactive Neurons Within the Mucosa, Not the Myenteric Plexus of Human Colon

British journal of biomedical science·7 Apr 2026