Brain atrophy rate

1. B vitamins decrease brain atrophy rate in members of the 'ins/ins' group who were not using aspirin.

   “Notably, the supplements only slowed brain atrophy in members of the 'ins/ins' group who were not using aspirin.”

   Human trialin members of the 'ins/ins' group who were not using aspirin24 months

   The dihydrofolate reductase 19-bp deletion modifies the beneficial effect of B-vitamin therapy in mild cognitive impairment: pooled study of two randomized placebo-controlled trials

   Human molecular genetics·Nov 18, 2021

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1. Educational attainment was not clearly linked with brain atrophy rate in humans (longitudinal change, replicated across two independent samples).

   “despite marked mean atrophy in the cortex and hippocampus, education did not influence rates of change”

   Humanslongitudinal change, replicated across two independent samplescerebral cortex and hippocampus

   Educational attainment does not influence brain aging

   Proceedings of the National Academy of Sciences of the United States of America·Apr 28, 2021

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