Brain amyloid burden

3 papers5 findings

Effects

Relatively straight driving segments

upin humans1downin humans1

1 study

Brain amyloid burden increases relatively straight driving segments in humans (p < 0.05).
“the number and duration of “relatively straight” driving segments on single‐lane, low‐traffic roads with straight paths were consistently higher among Aβ‐positive drivers compared to Aβ‐negative ( p 's <0.05).”
Humanson single-lane, low-traffic roads with straight paths
Comparing the straightness of driving between senior drivers with elevated amyloid burden and those without
AAIC 2025 abstract25 Dec 2025
Brain amyloid burden impairs relatively straight driving segments in humans (p < 0.05).
“The number of “relatively straight” driving segments on high‐complexity, moderate to high traffic roads with winding paths were significantly lower among Aβ‐positive drivers than Aβ‐negative ( p < 0.05).”
Humanson high-complexity, moderate to high traffic roads with winding paths
Comparing the straightness of driving between senior drivers with elevated amyloid burden and those without
AAIC 2025 abstract25 Dec 2025

Driving speed

downin humans1

1 study

Brain amyloid burden decreases driving speed in humans (p < 0.05).
“The driving speed during “relatively straight” segments on certain single‐lane, low‐traffic roads was significantly lower among Aβ‐positive drivers ( p 's <0.05).”
Humanson certain single-lane, low-traffic roads
Comparing the straightness of driving between senior drivers with elevated amyloid burden and those without
AAIC 2025 abstract25 Dec 2025

Plasma Aβ42/Aβ40 ratio

upin humans1

1 study

Plasma Aβ42/Aβ40 ratio is associated with brain amyloid burden in humans.
“Significant correlations between plasma Aβ42/Aβ40 ratios and brain amyloid burden were reported, suggesting peripheral Aβ may reflect central pathology.”
Reviewplasma
The Role of Amyloid‐Beta in Blood and Cerebrospinal Fluid: Implications for Alzheimer’s Disease Diagnosis and Monitoring
AAIC 2025 abstract23 Dec 2025