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Bone copper

Biomarker

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Genes & Diseases·17 Mar

SIRT5 mediates the pro-osteogenic effects of estrogen through FDX1 demalonylation and cuproptosis inhibition in mesenchymal stem cells

Experiments in miceMechanisms
Paper

Related

  • FDX11
  • FDX1 demalonylation1
  • Lysosome1
  • Proteostasis1
  • SIRT51
  • SIRT5 expression1
  • Sex hormone signalling (oestrogen, androgen)1
  • Sirtuin signalling1
  • Stem cell differentiation1
  • Copper1
  • Estrogen1
  • Estrogen deficiency1
  • Postmenopausal osteoporosis1
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