Biological age difference

1 paper2 findings

Humans1

Associations

2

Hospitalization

upin humans1

1 study

Biological age difference predicts hospitalization in humans (IRR 1.06, 95% CI 1.03-1.09).
“and a 6% higher hospitalization rate (incidence rate ratio 1.06, 95% CI 1.03-1.09).”
Humansn = 2,597
Difference between Biological Age and Chronological Age Predicts Mortality and Hospitalization in a Longitudinal Adult Cohort
Aging and disease17 May 2026

Mortality

upin humans1HR 1.15

1 study

Biological age difference predicts mortality in humans (HR 1.15, 95% CI 1.10-1.21).
“Each 1-year increase in Agediff was associated with a 15% higher mortality hazard (HR 1.15, 95% CI 1.10-1.21)”
Humansn = 2,597
Difference between Biological Age and Chronological Age Predicts Mortality and Hospitalization in a Longitudinal Adult Cohort
Aging and disease17 May 2026

Latest

9 in 12 months

bioRxiv24 Sep

System-Specific Epigenetic Aging Signatures in Autistic Adults

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The Journals of Gerontology, Series A2 Jul

The contribution of social and economic factors to accelerated biological aging differences between non-Hispanic Black and White adults in the Health and Retirement Study

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NPJ Science of Food25 Jun

Urinary caffeine and caffeine metabolites, biological aging, and cardiovascular-kidney-metabolic syndrome: deciphering association, mediation, and mechanism via epidemiology and bioinformatics

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BMJ Mental Health23 Jun

Metabolomic ageing across mental and behavioural disorders

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Aging and Disease3 Jun

Difference between Biological Age and Chronological Age Predicts Mortality and Hospitalization in a Longitudinal Adult Cohort

Cohort study of 2,597 peopleBiological age

The Journal of Nutrition, Health & Aging8 May

Biological age acceleration, genetic susceptibility, and incident diabetic retinopathy risk: A prospective cohort study

Cohort study of 12,608 peopleBiological-age acceleration

Journal of Affective Disorders5 Apr

Accelerated biological aging (GOLD BioAgeDiff) and depressive symptoms in US adults: NHANES 2005-2018

Cross-sectional study of 14,318 peopleDepressive symptoms

Annals of Epidemiology14 Mar

Phenotypic age acceleration through a lens of intersectional inequalities in the German National Cohort (NAKO)

Cohort study of 173,925 peoplePopulations

Journal of Hypertension12 Mar

Biological age acceleration in primary aldosteronism: associations with renin, aldosterone, aldosterone-to-renin ratio, and left ventricular mass index

Cross-sectional study of 1,201 peopleLeft ventricular mass index

bioRxiv3 Oct

Biological age acceleration is more prevalent in men than in women at time of spontaneous intracerebral hemorrhage

Preprint: cross-sectional study of 657 peopleEpigenetic age

Biological age1