Biological age clocks

Biomarker

1 paper

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bioRxiv

Mechanistic biological age clock matches PhenoAge in predicting human mortality

The systems pharmacology model splits biological age into organ axes, revealing that pharmacological drops in inflammation may not translate to expected risk reductions.The systems pharmacology model splits biological age into organ axes, revealing that pharmacological drops in inflammation may not translate to expected risk reductions.

Preprint: cohort study of 24,650 peoplePhenoAge
Science Advances

Speech age gaps track dementia phenotypes and biological aging

In 2,928 individuals across five Latin American countries, speech age gaps tracked dementia diagnoses, brain age, social exposome, and epigenetic aging clocks.In 2,928 individuals across five Latin American countries, speech age gaps tracked dementia diagnoses, brain age, social exposome, and epigenetic aging clocks.

Cohort study of 2,928 peopleFrontotemporal dementia
medRxiv

Biological age uncertainty independently predicts mortality and health decline in humans

Researchers derived biological age uncertainty across UK Biobank participants, finding that higher uncertainty reflects reduced physiological coherence and predicts worse…Researchers derived biological age uncertainty across UK Biobank participants, finding that higher uncertainty reflects reduced physiological coherence and predicts worse health outcomes.

Preprint: cohort study of 450,000 peopleBiomarkers