Bilirubin degradation metabolite C16H18N2O5

1. Bilirubin degradation metabolite C16H18N2O5 mediates total testosterone in humans (mediation proportion = -68.0%, P = .016).

   “Mediation analysis detected bilirubin degradation metabolite C16H18N2O5 (2) as a negative mediator (mediation proportion = -68.0%, P = .016).”

   Humansiron to total testosteronemales

   Serum Minerals and Male Age-related Hypogonadism: Multimodal Evidence Decoding Associations and Intervention Strategies

   The Journal of clinical endocrinology and metabolism·20 Sep 2025

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