β-amyloid burden

1. Physical activity decreases β-amyloid burden in humans (p = 0.014).

   “physically active individuals exhibited a lesser degree of biomarker alterations compared with the physically inactive”

   Humanswith advancing agebrain

   Physical activity attenuates age-related biomarker alterations in preclinical AD

   Neurology·8 Oct 2014

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1. β-amyloid burden is associated with white matter hyperintensities in humans.

   “all cohorts except SCAN showed significant associations between age‐adjusted WMH volume and CLs”

   Humanscognitively normal

   White matter hyperintensities and Alzheimer's disease pathology in heterogeneous cohorts

   AAIC 2025 abstract·24 Dec 2025

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