Bacterial DNA

Biomarker

4 papers study it16 more mention it5 findings

  • Humans1
  • Animals3

Interventions

1

Antibiotics

downin mice1

1 study
  1. Antibiotics decrease bacterial DNA in mice.

    “Antibiotic treatment remarkably reduced bacterial DNA abundance in ageing mice.”

    Animalsageing

    Gut lumen-leaked microbial DNA causes myocardial inflammation and impairs cardiac contractility in ageing mouse heart

    Frontiers in immunologyJul 13, 2023

More on Antibiotics

Associations

4

Biological age

upin humans1

1 study
  1. Bacterial DNA is associated with biological age in humans.

    “Additionally, BB-DNA was positively associated with DNAm-based biological age estimators, particularly DNAmPhenoAge and DNAmAge Skin Blood Clock.”

    Humansn = 285

    Circulating Bacterial DNA as a Novel Blood-Based Biomarker in Type 2 Diabetes Mellitus (DM2): Results from the PROMOTERA Study

    International journal of molecular sciencesJul 8, 2025

DNAmTL

downin humans1

1 study
  1. Bacterial DNA is associated with DNAmTL in humans.

    “Epigenetic analysis revealed a negative correlation between BB-DNA and DNA methylation-based leukocyte telomere length, suggesting accelerated aging in DM2.”

    Humansn = 285

    Circulating Bacterial DNA as a Novel Blood-Based Biomarker in Type 2 Diabetes Mellitus (DM2): Results from the PROMOTERA Study

    International journal of molecular sciencesJul 8, 2025

More on DNAmTL

IL-1β

upin humans1

1 study
  1. Bacterial DNA is associated with IL-1β in humans.

    “BB-DNA showed a positive association with plasma IL-1β, linking bacterial DNA to systemic inflammation.”

    Humansplasman = 285

    Circulating Bacterial DNA as a Novel Blood-Based Biomarker in Type 2 Diabetes Mellitus (DM2): Results from the PROMOTERA Study

    International journal of molecular sciencesJul 8, 2025

More on IL-1β

Type 2 diabetes

upin humans1

1 study
  1. Bacterial DNA is associated with type 2 diabetes in humans.

    “BB-DNA levels were higher in DM2 patients than in non-diabetic subjects, with the highest levels in those with severe renal impairment.”

    HumansDM2 patients vs non-diabetic subjectsn = 285

    Circulating Bacterial DNA as a Novel Blood-Based Biomarker in Type 2 Diabetes Mellitus (DM2): Results from the PROMOTERA Study

    International journal of molecular sciencesJul 8, 2025

More on Type 2 diabetes

Funding

1 grant since 2022

National Cancer InstituteUS$221.6k

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 1May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 12 papers in 12 months