Autoimmunity-related CD4+ central memory T cell subpopulation abundance

Age is associated with autoimmunity-related CD4+ central memory T cell subpopulation abundance in humans.

“female CD4+ central memory T cells exhibit abundance shifts in subpopulations involved in autoimmunity alongside age-associated transcriptional signatures enriched for autoimmune-related pathways.”

Humansperipheral blood mononuclear cellfemales

Single-cell atlas of the human immune system reveals sex-specific dynamics of immunosenescence

bioRxiv (Cold Spring Harbor Laboratory)·8 Nov 2024Preprint