Australian National University-Alzheimer's Disease Risk Index

There are 10 papers on Australian National University-Alzheimer's Disease Risk Index in aging research: 3 trials and 5 observational studies in people, 1 review.

Biomarker

10 papers study it3 more mention it11 findings

1 new paper in 30 daysSee all 13 papers on Australian National University-Alzheimer's Disease Risk Index

“A higher ANU-ADRI was significantly related to worse cognition, at baseline (e.g., estimate for global cognition [95% confidence interval] was -0.028 [-0.032 to -0.025])”
The Australian National University Alzheimer's Disease Risk Index (ANU-ADRI) score as a predictor for cognitive decline and potential surrogate outcome in the FINGER lifestyle randomized controlled trialEuropean journal of neurology2024doi:10.1111/ene.16238
  • Human trial3
  • Humans5

Interventions

1

Multidomain lifestyle intervention

no changein humans1

1 study
  1. Multidomain lifestyle intervention showed no clear effect on Australian National University-Alzheimer's Disease Risk Index in humans.

    “The full score increased for both groups with no significant difference.”

    Human trial2 yearsn = 1,174

    The Australian National University Alzheimer's Disease Risk Index (ANU-ADRI) score as a predictor for cognitive decline and potential surrogate outcome in the FINGER lifestyle randomized controlled trial

    European journal of neurology

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Associations

6

Dementia

upin humans2

2 studies
  1. Australian National University-Alzheimer's Disease Risk Index predicts dementia in humans (C statistic 0.59 (95% CI, 0.58-0.60)).

    “0.59 (95% CI, 0.58-0.60) for ANU-ADRI”

    Humans10 yearsn = 465,929

    Estimating Dementia Risk Using Multifactorial Prediction Models

    JAMA network open

  2. Australian National University-Alzheimer's Disease Risk Index predicts dementia in an Australian cohort (AUC 0.65 (95% CI 0.60-0.70)).

    “The discrimination of the models was 0.65 (95% CI 0.60-0.70), 0.65 (95% CI 0.60-0.71), 0.54 (95% CI 0.49-0.58) and 0.80 (95% CI 0.78-0.83), respectively.”

    Humansin an Australian cohort7.1 yearsn = 3,306

    Validity of three risk prediction models for dementia or cognitive impairment in Australia

    Age and ageing

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Cognitive function

downin humans1

1 study
  1. Australian National University-Alzheimer's Disease Risk Index predicts cognitive function in humans (per-year changes in cognition) (-0.004, 95% CI -0.006 to -0.003).

    “The direction of the association estimates consistently indicated that a higher/increased ANU‐ADRI risk score significantly correlated with worse cognition.”

    Human trialper-year changes in cognition2 yearsn = 1,174

    The Australian National University Alzheimer's Disease Risk Index (ANU-ADRI) score as a predictor for cognitive decline and potential surrogate outcome in the FINGER lifestyle randomized controlled trial

    European journal of neurology

  2. Australian National University-Alzheimer's Disease Risk Index is associated with cognitive function in humans (cross-sectionally at baseline) (-0.028, 95% CI -0.032 to -0.025).

    “The direction of the association estimates consistently indicated that a higher/increased ANU‐ADRI risk score significantly correlated with worse cognition.”

    Human trialcross-sectionally at baseline2 yearsn = 1,174

    The Australian National University Alzheimer's Disease Risk Index (ANU-ADRI) score as a predictor for cognitive decline and potential surrogate outcome in the FINGER lifestyle randomized controlled trial

    European journal of neurology

  3. Australian National University-Alzheimer's Disease Risk Index predicts cognitive function in humans (at risk of dementia) (estimate -0.068, 95% CI -0.108 to -0.026).

    “estimate for 2-year changes in ANU-ADRI and per-year changes in global cognition [95% confidence interval] was -0.068 [-0.026 to -0.108]”

    Human trialat risk of dementia2-yearn = 1,174

    The Australian National University Alzheimer's Disease Risk Index (ANU-ADRI) score as a predictor for cognitive decline and potential surrogate outcome in the FINGER lifestyle randomized controlled trial

    European journal of neurology

  4. Australian National University-Alzheimer's Disease Risk Index is associated with cognitive function in humans (at risk of dementia) (estimate -0.028, 95% CI -0.032 to -0.025).

    “A higher ANU-ADRI was significantly related to worse cognition, at baseline (e.g., estimate for global cognition [95% confidence interval] was -0.028 [-0.032 to -0.025])”

    Human trialat risk of dementia2-yearn = 1,174

    The Australian National University Alzheimer's Disease Risk Index (ANU-ADRI) score as a predictor for cognitive decline and potential surrogate outcome in the FINGER lifestyle randomized controlled trial

    European journal of neurology

Timed Up and Go test

upin humans1

1 study
  1. Australian National University-Alzheimer's Disease Risk Index is associated with Timed Up and Go test in humans (geriatric outpatients) (r = 0.538, p < 0.001).

    “a moderate positive linear association was found between the ANU-ADRI and the Timed Up and Go Test duration (r = 0.538, p < 0.001).”

    Humansgeriatric outpatientsn = 339

    Validity and reliability of the Turkish version of the Australian National University-Alzheimer's Disease Risk Index (ANU-ADRI)

    Applied neuropsychology. Adult

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Performance-Oriented Mobility Assessment

downin humans1

1 study
  1. Australian National University-Alzheimer's Disease Risk Index is associated with Performance-Oriented Mobility Assessment in humans (geriatric outpatients) (r = -0.406, p < 0.001).

    “POMA (r = -0.406, p < 0.001)”

    Humansgeriatric outpatientsn = 339

    Validity and reliability of the Turkish version of the Australian National University-Alzheimer's Disease Risk Index (ANU-ADRI)

    Applied neuropsychology. Adult

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Mini-Mental State Examination

downin humans1

1 study
  1. Australian National University-Alzheimer's Disease Risk Index is associated with Mini-Mental State Examination in humans (geriatric outpatients) (r = -0.310, p < 0.001).

    “there existed a moderate negative linear association between the ANU-ADRI and MMSE scores (r = -0.310, p < 0.001)”

    Humansgeriatric outpatientsn = 339

    Validity and reliability of the Turkish version of the Australian National University-Alzheimer's Disease Risk Index (ANU-ADRI)

    Applied neuropsychology. Adult

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Test-retest reliability

upin humans1

1 study
  1. Australian National University-Alzheimer's Disease Risk Index is associated with test-retest reliability in humans (geriatric outpatients) (r = 0.997, p < 0.001).

    “A correlation was observed between the mean scores of the ANU-ADRI test and retest (r = 0.997, p < 0.001).”

    Humansgeriatric outpatientsn = 339

    Validity and reliability of the Turkish version of the Australian National University-Alzheimer's Disease Risk Index (ANU-ADRI)

    Applied neuropsychology. Adult

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See all 13 papers on Australian National University-Alzheimer's Disease Risk Index