ATV TfR brain uptake

Biomarker

1 paper1 finding

  • Humans1

Upstream

1

Alzheimer's disease

no changein mice1

1 study
  1. Alzheimer's disease has no effect on ATV TfR brain uptake in mice.

    “Additionally, neither TfR expression nor ATV TfR brain uptake changed significantly in 5xFAD mice.”

    Animals5xFAD mouse model receiving ATV TfRbrain

    Transferrin receptor-mediated transport at the blood-brain barrier is elevated during early development but maintained across adult aging

    bioRxiv (Cold Spring Harbor Laboratory)14 Nov 2024Preprint

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