ATV TfR brain exposure

1 paper1 finding

Humans1

Associations

1

Early development

upin mice1

1 study

Early development is associated with ATV TfR brain exposure in mice (Highest brain exposure in neonates).
“Healthy neonates exhibited the highest vascular TfR expression and ATV TfR brain exposure, whereas BBB transport capacity remained stable across adulthood.”
Animalshealthy mice receiving ATV TfRbrain
Transferrin receptor-mediated transport at the blood-brain barrier is elevated during early development but maintained across adult aging
bioRxiv (Cold Spring Harbor Laboratory)14 Nov 2024Preprint

Latest

bioRxiv14 Nov

Transferrin receptor-mediated transport at the blood-brain barrier is elevated during early development but maintained across adult aging

Preprint: study in peopleInterventions