Apolipoprotein B48

1. Apolipoprotein B48 lowers the risk of Alzheimer's disease in humans (HR 0.78 (95% CI 0.66-0.93)).

   “a SDU increase in ln(ApoB48) concentration was associated with a 22% decrease in the risk for incident AD (HR [95% CI] = 0.78 [0.66, 0.93])”

   Humansblood12.55 yearsn = 822

   Blood Lipoprotein Concentrations and Risk of Alzheimer's Disease. The Framingham Heart Study

   AAIC 2025 abstract·25 Dec 2025

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