Apolipoprotein B-100 fractional catabolic rate

1. Menopause decreases apolipoprotein B-100 fractional catabolic rate in humans (P<0.05).

   “These differences were accounted for by lower TRL, IDL, and LDL apoB-100 FCR (P<0.05), with no difference in PR.”

   Human trialfed state after 6 weeks on standardized Western dietplasmafemales

   TRL, IDL, and LDL apolipoprotein B-100 and HDL apolipoprotein A-I kinetics as a function of age and menopausal status

   Arteriosclerosis, thrombosis, and vascular biology·2 Jun 2005

1. Apolipoprotein B-100 fractional catabolic rate is associated with LDL cholesterol in humans (r=-0.70, P<0.001).

   “Plasma LDL-C concentrations were negatively correlated with LDL apoB-100 FCR (r=-0.70; P<0.001) but not PR.”

   Human trialfed state after 6 weeks on standardized Western dietplasmafemales

   TRL, IDL, and LDL apolipoprotein B-100 and HDL apolipoprotein A-I kinetics as a function of age and menopausal status

   Arteriosclerosis, thrombosis, and vascular biology·2 Jun 2005

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