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Aortic valve calcium

There are 6 papers on aortic valve calcium in aging research: 6 observational studies in people. The newest story, Nov 9, 2026: “Exercise volume was not linked to heart valve calcium”.

Biomarker

6 papers study it2 more mention it5 findings

3 new papers in 30 daysSee all 8 papers on aortic valve calcium

“The association of AVC with moderate-severe AS was significant for all race and ethnicity groups: White hazard ratio, 1.82 (95% CI, 1.62-2.03)”
Race and Ethnic-Specific Burden of Aortic Valve Calcium and Its Association With Long-Term Aortic Stenosis: Multi-Ethnic Study of AtherosclerosisCirculation. Cardiovascular imaging2026doi:10.1161/circimaging.125.018916
  • Humans6

Interventions

1

Physical activity

no changein humans1

1 study

  1. Physical activity was not clearly linked with aortic valve calcium in humans.

    “No association was found between PA volume and AVC in the overall study population.”

    Humansaortic valven = 26,424

    Exercise volume was not linked to heart valve calcium

    AHA Scientific Sessions 2026 abstract

More on Physical activity

Associations

3

Aortic valve stenosis

upin humans2HR 1.82–13.37

2 studies

  1. Aortic valve calcium is linked with a higher risk of aortic valve stenosis in humans (HR 1.82 (95% CI, 1.62-2.03)).

    “The association of AVC with moderate-severe AS was significant for all race and ethnicity groups: White hazard ratio, 1.82 (95% CI, 1.62-2.03)”

    Humansmedian follow-up of 16.7 yearsn = 6,812

    Race and Ethnic-Specific Burden of Aortic Valve Calcium and Its Association With Long-Term Aortic Stenosis: Multi-Ethnic Study of Atherosclerosis

    Circulation. Cardiovascular imaging

  2. Aortic valve calcium is linked with a higher risk of aortic valve stenosis in humans (HR 13.37; 95% CI 5.67-31.52).

    “AVC >0 was associated with a similar significantly higher risk of incident moderate-severe AS for both younger (HR 13.37; 95% CI 5.67-31.52) and older participants (HR 10.59, 95% CI 6.77-16.56).”

    Humansmedian follow-up of 16 yearsn = 3,834

    Impact of age on aortic valve calcium progression and risk for aortic stenosis: multi-ethnic study of atherosclerosis

    European heart journal. Cardiovascular Imaging

More on Aortic valve stenosis

Oxidized phospholipids

mixedin humans1

1 study

  1. Oxidized phospholipids are associated with aortic valve calcium in humans (free of cardiovascular disease).

    “For Lp(a) and OxPL, we only observed significant associations with odds of AVC.”

    Humansfree of cardiovascular diseaseaortic valven = 1,207

    Cardiovascular Health and Lipoprotein(a)/Oxidized Phospholipids in Relation to Subclinical and Clinical Cardiovascular Disease: The Framingham Heart Study

    AHA Scientific Sessions 2026 abstract

More on Oxidized phospholipids

Lipoprotein

mixedin humans1

1 study

  1. Lipoprotein is associated with aortic valve calcium in humans (free of cardiovascular disease).

    “For Lp(a) and OxPL, we only observed significant associations with odds of AVC.”

    Humansfree of cardiovascular diseaseaortic valven = 1,207

    Cardiovascular Health and Lipoprotein(a)/Oxidized Phospholipids in Relation to Subclinical and Clinical Cardiovascular Disease: The Framingham Heart Study

    AHA Scientific Sessions 2026 abstract

More on Lipoprotein

Latest

Dec 2025: 0Jan 2026: 1Feb 2026: 1Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 35 papers in 12 months
AHA Scientific Sessions 2026 Abstract

Exercise volume was not linked to heart valve calcium

Among 26,424 adults aged 40–80, an observational analysis found no link between reported exercise volume and calcium deposits on the aortic valve.Among 26,424 adults aged 40–80, an observational analysis found no link between reported exercise volume and calcium deposits on the aortic valve.

Cross-sectional · 26,424 peoplePopulations
Paper
European Heart Journal

Aspirin linked to lower valve disease risk in some adults

At lipoprotein(a) levels of at least 75 mg/dL, aspirin use was linked to lower risk of new valve calcium versus nonuse (hazard ratio 0.42).At lipoprotein(a) levels of at least 75 mg/dL, aspirin use was linked to lower risk of new valve calcium versus nonuse (hazard ratio 0.42).

Cohort · 6,598 peopleAspirin
Paper

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