Antibody avidity

Biomarker

3 papers3 findings

  • Humans3

Interventions

1

Tozinameran

no changein humans1upin humans1

1 study
  1. Tozinameran has no effect on antibody avidity in humans.

    “Avidity significantly increased after the 1st booster but not for subsequent boosters.”

    Humanssubsequent boosters

    Avidity maturation of humoral response following primary and booster doses of BNT162b2 mRNA vaccine among nursing home residents and healthcare workers

    GeroScienceMay 25, 2024

  2. Tozinameran increases antibody avidity in humans.

    “Avidity significantly increased after the 1st booster but not for subsequent boosters.”

    Humansafter 1st booster

    Avidity maturation of humoral response following primary and booster doses of BNT162b2 mRNA vaccine among nursing home residents and healthcare workers

    GeroScienceMay 25, 2024

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Upstream

1

Cytomegalovirus infection

downin humans1

1 study
  1. Cytomegalovirus infection decreases antibody avidity in humans.

    “lower VZV-gE-specific antibody avidity in ZVL recipients”

    Human trialin ZVL recipients

    The Reduced Immunogenicity of Zoster Vaccines in CMV-Seropositive Older Adults Correlates with T Cell Imprinting

    VaccinesMar 22, 2025

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