Amyloid β42/β40 ratio

1. Perivascular spaces are associated with amyloid β42/β40 ratio in humans (p < 0.05).

   “and inversely correlated with Aβ42/40 ratio[a lower ratio indicating greater amyloid burden]( p <0.05).”

   Humansadjusted for age, gender, education, and APOE ε4 statusbasal ganglian = 979

   Perivascular Spaces as Early Indicators of Alzheimer's Pathology and Cognitive Impairment in a Southeast Asian Cohort: Insights from the BIOCIS Study

   AAIC 2025 abstract·24 Dec 2025

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