Ammonia accumulation

1 paper1 finding

Model organisms1

Upstream

1

CCHa1

downin flies1

1 study

CCHa1 decreases ammonia accumulation in flies.
“impairment of the CCHa1-mediated gut-enteric neuronal axis results in ammonia accumulation and a shortened lifespan under HPD conditions.”
Model organismsunder high-protein diet conditions, shown by impairment of the CCHa1-mediated gut-enteric neuronal axis
A high-protein diet-responsive gut hormone regulates behavioral and metabolic optimization in Drosophila melanogaster
Nature communications30 Dec 2024

Latest

1 in 12 months

Cureus11 Aug

Effect of an Integrated Exercise Training Program on Muscle Mass and Functional Capacity in Sarcopenic Patients With Decompensated Liver Cirrhosis

Randomised trial in 40 peopleExercise

Insect Science15 Sep

Purine nucleoside phosphorylase mediates midgut physiological functions in Aedes aegypti by orchestrating uric acid biosynthesis and oxidative stress homeostasis

Experiments in model organismsMechanisms

Nature Communications31 Dec

A high-protein diet-responsive gut hormone regulates behavioral and metabolic optimization in Drosophila melanogaster

Experiments in fliesGut and microbiome