Alpha-synucleinopathy

Biomarker

1 paper

  • Humans1

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Alzheimer's Research & Therapy

Probable REM sleep disorder links to Lewy body dementia

In a memory clinic cohort, probable REM sleep behaviour disorder was linked to incident Lewy body dementia with a hazard ratio of 4.82.In a memory clinic cohort, probable REM sleep behaviour disorder was linked to incident Lewy body dementia with a hazard ratio of 4.82.

Cohort study of 5,274 peopleDementia
Sleep Medicine

Dopamine loss in sleep disorder predicts Parkinson conversion

In PET scans of 77 patients with isolated REM sleep behavior disorder, quantitative dopamine markers showed intermediate loss and predicted phenoconversion toward…In PET scans of 77 patients with isolated REM sleep behavior disorder, quantitative dopamine markers showed intermediate loss and predicted phenoconversion toward Parkinson's disease.

Cohort study of 194 peopleParkinson's disease