Alpha-hydroxy-5-methyl-tetrahydrofolate

1. Alpha-hydroxy-5-methyl-tetrahydrofolate is associated with grip strength in humans (r = -0.21).

   “Only hm-THF was correlated with grip strength (r = -0.21) and differed between the low group and the random sample.”

   Humansplasmamales

   Nutrient Metabolites Associated With Low D3Cr Muscle Mass, Strength, and Physical Performance in Older Men

   The journals of gerontology. Series A, Biological sciences and medical sciences·Sep 11, 2023

1. Alpha-hydroxy-5-methyl-tetrahydrofolate is associated with D3Cr muscle mass in humans (r = -0.25, p < .001).

   “For D3Cr muscle mass, significant biomarkers (p < .001) with ≥10% fold difference and largest partial correlations were tryptophan (Trp; r = 0.31), kynurenine (Kyn)/Trp; r = -0.27), nicotinamide (Nam)/quinolinic acid (Quin; r = 0.21), and alpha-hydroxy-5-methyl-tetrahydrofolate (hm-THF; r = -0.25).”

   Humansplasmamales

   Nutrient Metabolites Associated With Low D3Cr Muscle Mass, Strength, and Physical Performance in Older Men

   The journals of gerontology. Series A, Biological sciences and medical sciences·Sep 11, 2023

More on D3Cr muscle mass