Aging- and neurodegeneration-associated transcriptional programs

1. Lysergic acid diethylamide is associated with aging- and neurodegeneration-associated transcriptional programs in silico.

   “we show that LSD induces gene expression patterns strongly anti-correlated with aging and neurodegeneration programs.”

   In silicoRodent LSD-induced profiles compared with human prefrontal cortex aging- and dementia-associated expression changesbrainchronic treatment

   Lysergic acid diethylamide reverses aging- and neurodegeneration-associated brain transcriptional programs

   bioRxiv (Cold Spring Harbor Laboratory)·29 May 2026Preprint

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