Aged microglia surrounding the plaque

1 paper1 finding

Animals1

Interventions

1

P16INK4A-SIRNA-LOADED nanoparticles

downin mice1

1 study

P16INK4A-SIRNA-LOADED nanoparticles decrease aged microglia surrounding the plaque in mice.
“reduced amyloid plaque formation and the number of aged microglia surrounding the plaque”
Animalsin 5XFAD mice
Rejuvenating aged microglia by p16ink4a-siRNA-loaded nanoparticles increases amyloid-β clearance in animal models of Alzheimer's disease
Molecular neurodegeneration16 Mar 2024

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Molecular Neurodegeneration17 Mar

Rejuvenating aged microglia by p16ink4a-siRNA-loaded nanoparticles increases amyloid-β clearance in animal models of Alzheimer's disease

Experiments in miceAlzheimer's disease