24-hour urinary sodium and chloride excretion

1. SGLT2 inhibitors + mineralocorticoid receptor antagonists are associated with 24-hour urinary sodium and chloride excretion in humans.

   “Group A exhibited increased 24 h urinary sodium and chloride excretion and lower urinary albumin excretion.”

   HumansHeart failure; initiation of combined therapy (Group A)30 days

   Combined SGLT-2 Inhibitor and Mineralocorticoid Receptor Antagonist Therapy: Effects on the Renin-Angiotensin-Aldosterone System in Heart Failure Treatment

   International journal of molecular sciences·24 Sep 2026

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