11β-HSD1 activity

1 paper1 finding

Animals1

Upstream

1

CRHR1

upin mice1

1 study

CRHR1 increases 11β-HSD1 activity in mice.
“In females, this increase is dependent on the presence of functional CRF1 receptors.”
Animalsaginghippocampusfemales
Genetic inactivation of the CRF₁ receptor eliminates age-linked elevation of hippocampal 11β-hydroxysteroid dehydrogenase type 1 activity in female mice
Journal of neuroendocrinology1 Jan 2026

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Genetic inactivation of the CRF₁ receptor eliminates age-linked elevation of hippocampal 11β-hydroxysteroid dehydrogenase type 1 activity in female mice

Experiments in miceMechanisms