79 results
In a mouse model of lung cancer, restricting food before tumour induction preserved lean mass and prolonged survival where targeting individual candidate factors failed.In a mouse model of lung cancer, restricting food before tumour induction preserved lean mass and prolonged survival where targeting individual candidate factors failed.
Experiments in mice with impaired DNA repair identified a female-specific metabolic pathway; a dietary supplement restored muscle force and metabolic profiles in females.Experiments in mice with impaired DNA repair identified a female-specific metabolic pathway; a dietary supplement restored muscle force and metabolic profiles in females.
In 1,095 sarcomere variant carriers, an AI-ECG model detected cardiomyopathy with an AUROC of 0.91 and predicted future disease with a hazard ratio of 1.55.In 1,095 sarcomere variant carriers, an AI-ECG model detected cardiomyopathy with an AUROC of 0.91 and predicted future disease with a hazard ratio of 1.55.
Cancer incidence rose modestly above baseline with adjusted hazard ratios of 1.05 to 1.08, while mortality followed a J-shaped pattern across serum vitamin B12 strata.Cancer incidence rose modestly above baseline with adjusted hazard ratios of 1.05 to 1.08, while mortality followed a J-shaped pattern across serum vitamin B12 strata.
Inhibiting the kinase reduced p62 UFMylation to promote ubiquitination and mitochondrial clearance, alleviating cognitive deficits in mice.Inhibiting the kinase reduced p62 UFMylation to promote ubiquitination and mitochondrial clearance, alleviating cognitive deficits in mice.