31 results
Pretrained on 10 million images, the model assessed 62 biomarkers across eight physiological systems, reaching a median Pearson's r of 0.172 across four cohorts.Pretrained on 10 million images, the model assessed 62 biomarkers across eight physiological systems, reaching a median Pearson's r of 0.172 across four cohorts.
In 602 discovery and 2,313 validation participants, associations between plasma pTau217 and brain pathology were stronger among people with lower periventricular…In 602 discovery and 2,313 validation participants, associations between plasma pTau217 and brain pathology were stronger among people with lower periventricular diffusivity.
In transgenic mice, exercise prevented doxorubicin-induced cardiotoxicity and senescence while maintaining cardiac FNDC5 levels, with irisin blunting senescence in…In transgenic mice, exercise prevented doxorubicin-induced cardiotoxicity and senescence while maintaining cardiac FNDC5 levels, with irisin blunting senescence in cultured human cells.
The compound targets Ero1L to stabilize contacts between mitochondria and the endoplasmic reticulum, mitigating tissue damage in cells and mice.The compound targets Ero1L to stabilize contacts between mitochondria and the endoplasmic reticulum, mitigating tissue damage in cells and mice.
The compound directly binds Prohibitin-2 to activate PINK1-PRKN-dependent clearance of damaged mitochondria, easing motor deficits in transgenic mice.The compound directly binds Prohibitin-2 to activate PINK1-PRKN-dependent clearance of damaged mitochondria, easing motor deficits in transgenic mice.