Gerald de Haan
University Medical Center Groningen
Also published as: G de Haan
21 papersORCID 0000-0001-9706-0138OpenAlex
- Stem cell maintenance
- Cell cycle regulation
- Epigenetic regulation of gene expression
- DNA methylation
- SELP
- Plasma membrane
- Cellular senescence
- Histone modification and chromatin remodeling
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Papers
Nature Aging
Aberrant engagement of P-selectin drives hematopoietic stem cell aging in mice
Experiments in miceBlood and immune system
Methods in Molecular Biology
Polychromatic Flow Cytometry to Identify Rare Aged Hematopoietic Stem Cell Subpopulations
Study protocolBlood and immune system
Blood Advances
CD61 identifies a superior population of aged murine HSCs and is required to preserve quiescence and self-renewal
Experiments in miceMechanisms
Nature Communications
Taz protects hematopoietic stem cells from an aging-dependent decrease in PU.1 activity
Experiments in miceBlood and immune system
Nature Communications
Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1
Experiments in miceBlood and immune system
Scientific Reports
Targeted methods for epigenetic age predictions in mice
Experiments in miceBiomarkers
Nederlands Tijdschrift Voor Geneeskunde
Clonal hematopoiesis: a risk factor for leukemia and cardiovascular disease?
ReviewMechanisms
Experimental Hematology
Lifelong dietary intervention does not affect hematopoietic stem cell function
Experiments in animalsBlood and immune system
Experimental Hematology
Hematopoiesis during development, aging, and disease
ReviewBlood and immune system
FASEB Journal
Genetic analysis of hemopoietic cell cycling in mice suggests its involvement in organismal life span
Experiments in miceMechanisms
The Journal of Experimental Medicine
Intrinsic and extrinsic control of hemopoietic stem cell numbers: mapping of a stem cell gene
Experiments in miceMechanisms
Works at
Universitair Medisch Centrum Groningen
Lead investigator
Sources: openalex.org
Grants and prizes
Nederlandse Organisatie voor Wetenschappelijk Onderzoek
Open Competitie ENW - M 2020/2021 M20-1, Identification and functional characterization of hematopoietic stem cell aging genes, OCENW.M20.002, 2022, Mar 1, 2022
Sources: openalex.org
Earlier work
- Experimental Hematology2025
3080 – TRACKING THE BONE MARROW INTERACTOME OF HEMATOPOIETIC STEM CELLS
- Experimental Hematology2025
3022 – COMPARING IN VITRO HUMAN PLURIPOTENT STEM CELL MODELS TO ASSESS HEMATOPOIETIC DEVELOPMENT
- Experimental Hematology2025
3021 – EX VIVO EXPANSION OF HEMATOPOIETIC PROGENITOR CELLS DERIVED FROM INDUCED PLURIPOTENT STEM CELLS
- Experimental Hematology2025
3181 – ABERRANT ENGAGEMENT OF P-SELECTIN DRIVES HEMATOPOIETIC STEM CELL AGING
- Experimental Hematology2025
3099 – CYTOPLASMIC LOCALIZATION OF THE POLYCOMB PROTEIN CBX7 BLOCKS LEUKEMIC CELL GROWTH