Albert C. Shaw

Yale University

Also published as: Albert Shaw

17 papersORCID 0000-0003-4970-7640 OpenAlex

Yale University

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Papers

Nature AgingApr 14

Exoproteome of calorie-restricted humans identifies complement deactivation as an immunometabolic checkpoint reducing inflammaging

Randomized trial in peopleDietary restriction

GSA 2025 AbstractJan 3

Multiparameter Profiling Distinguishes Functional Subsets of Platelets in Aging

Cohort study in peopleMechanisms

bioRxivJun 12

Hormetic elevation of taurine restrains inflammaging by deactivating the NLRP3 inflammasome

Preprint: non-randomized trial in peopleInterventions

AgingAug 22

Dectin-1 stimulation promotes a distinct inflammatory signature in the setting of HIV-infection and aging

Cohort study in peopleInflammation

AgingJun 27

High-throughput single-cell profiling of B cell responses following inactivated influenza vaccination in young and older adults

Study in peopleImmune response

Aging CellJan 20

Platelet response to influenza vaccination reflects effects of aging

Study in peopleImmune response

Aging CellAug 30

Alterations in high-dimensional T-cell profile and gene signature of immune aging in HIV-infected older adults without viremia

Cross-sectional study in peopleImmune response

Aging CellAug 24

Metabolomic and transcriptomic signatures of influenza vaccine response in healthy young and older adults

Cohort study in peopleTryptophan–kynurenine metabolism

Interdisciplinary Topics in Gerontology and GeriatricsApr 16

How Inflammation Blunts Innate Immunity in Aging

ReviewMechanisms

Journal of ImmunologyFeb 16

Seasonal Variability and Shared Molecular Signatures of Inactivated Influenza Vaccination in Young and Older Adults

Study in peopleMechanisms

Aging CellMay 3

Transcriptomic analysis of human IL-7 receptor alpha low and high effector memory CD8⁺ T cells reveals an age-associated signature linked to influenza vaccine response in older adults

Study in peopleMechanisms

Clinical ImmunologyJan 20

Dissecting alterations in human CD8+ T cells with aging by high-dimensional single cell mass cytometry

Study in peopleMechanisms

The Journals of Gerontology, Series ASep 22

Impact of Aging and HIV Infection on the Function of the C-Type Lectin Receptor MINCLE in Monocytes

Cohort study in peopleMechanisms

Science SignalingDec 14

Aging impairs both primary and secondary RIG-I signaling for interferon induction in human monocytes

Experiments in cellsMechanisms

Cell ReportsFeb 28

β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares

Experiments in animalsInterventions

Clinics in Geriatric MedicineJul 10

Host Resistance and Immune Aging

ReviewImmune response

PNASMay 21

Development of autoimmunity in mice lacking DNA topoisomerase 3beta

Experiments in miceMechanisms

Works at

Yale University
Professor of medicine

Sources: reporter.nih.gov

Grants and prizes

National Institute of Allergy and Infectious Diseases
R01, Circadian Rhythms and Innate Immune Response in Aging, R01AI142624, 2019–2025, Jan 12, 2023
National Institute on Aging
K24, Midcareer Award in Translational Immunology of Aging, K24AG042489, 2012–2023, Jun 10, 2022
National Institute on Aging
R01, The Impact of Aging and HIV Infection on Immunologic and Transcriptomic Signatures of Influenza Vaccine Response, R01AG055362, 2017–2023, Jun 9, 2021

Sources: reporter.nih.gov