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Research Square

TyGFI Predicts Depression in Pre-diabetes: A LightGBM and SHAP Analysis of CHARLS and NHANES

By Xueqian Hu, Yibo Dai, Wenxi Sun, Xueyan Bao
Preprint: cohort study of 1,887 peopleBiomarkers
Paper
  • Insulin/IGF-1 signalling
  • Lipid and ceramide metabolism
  • TyGFI
  • Depression
  • Prediabetes
  • Humans

The paper

Xueqian Hu, Yibo Dai, Wenxi Sun, Xueyan Bao

Shanghai Changning Mental Health Center; Fudan University

Research Square, 11 Sep 2026, Preprint, not peer-reviewed

doi.org/10.21203/rs.3.rs-10580270/v1

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