TyGFI

Biomarker

2 papers4 findings

Human cohort preprints associate TyGFI with stroke risk in Chinese adults with arthritis and with depression in CHARLS participants with pre-diabetes. Depression prediction is also reported in CHARLS and NHANES participants with pre-diabetes; stroke risk is higher in the highest versus lowest TyGFI tertile.

  • Humans2

Associations

2

Stroke

upin humans1HR 1.33

1 study
  1. TyGFI predicts stroke in humans (2.15-fold higher risk (95% CI 1.63–2.82)).

    Humansin Chinese adults with arthritis; highest vs lowest tertilemedian of 9 yearsn = 3,649

    Triglyceride–Glucose Index Combined with Frailty Index and Incident Stroke in Older Chinese Adults with Arthritis: A Prospective Cohort Study

    Research Square20 Sep 2026Preprint

  2. TyGFI raises the risk of stroke in humans (HR 1.33, 95% CI 1.22–1.47).

    Humansin Chinese adults with arthritismedian of 9 yearsn = 3,649

    Triglyceride–Glucose Index Combined with Frailty Index and Incident Stroke in Older Chinese Adults with Arthritis: A Prospective Cohort Study

    Research Square20 Sep 2026Preprint

More on Stroke

Depression

upin humans1OR 1.4

1 study
  1. TyGFI predicts depression in humans (AUCs of 0.813 and 0.976).

    Humansin CHARLS and NHANES participants with pre-diabetes

    TyGFI Predicts Depression in Pre-diabetes: A LightGBM and SHAP Analysis of CHARLS and NHANES

    Research Square11 Sep 2026Preprint

  2. TyGFI is associated with depression in humans (OR 1.40, 95% CI 1.26–1.55).

    Humansin adults with pre-diabetes in CHARLSn = 1,887

    TyGFI Predicts Depression in Pre-diabetes: A LightGBM and SHAP Analysis of CHARLS and NHANES

    Research Square11 Sep 2026Preprint

More on Depression

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