Research Square
Frailty and the Incidence of Major Ocular Diseases: A Prospective Cohort Study Integrating Proteomic Mediation Analysis
Preprint: cohort study in peoplePopulations
15.7 years
Abstract
Background The long-term association between frailty phenotype and major vision-threatening ocular diseases (age-related macular degeneration (AMD), diabetic retinopathy (DR), glaucoma, and cataract), as well as the underlying molecular mechanisms, remain unclear.
- Extracellular matrix remodelling
- Immune response
- Inflammation
- Age-related macular degeneration
- Cataract
- Humans
The paper
First Affiliated Hospital of Xi'an Jiaotong University; Xinjiang Medical University
Research Square, 18 Aug 2026, CC BY, Preprint, not peer-reviewed
