Research Square
Longitudinal multi-omic profiling of a pig-to-human lung xenograft reveals phased immune and tissue-remodeling responses
Preprint: case reportInterventions
9 days
Abstract
A prior clinical study showed that six-gene-edited pig lung xenografts transplanted into human decedents restricted hyperacute rejection and remained functional for nine days.
- Pig-to-human lung xenotransplantation
- Xenotransplantation
- Complement system
- Extracellular matrix remodelling
- Surfactant-associated proteins
- Humans
The paper
First Affiliated Hospital of Guangzhou Medical University; Guangzhou Laboratory
Research Square, 11 Aug 2026, CC BY, Preprint, not peer-reviewed
