Pig-to-human lung xenotransplantation

Intervention

1 paper3 findings

  • 1 lab in 1 country
  • 3 of 3 findings with company ties
  • Humans1

Outcomes

3

Complement system

upin humans1

1 study
  1. Pig-to-human lung xenotransplantation activates complement system in humans.

    “Early after reperfusion, BALF proteins showed terminal complement and coagulation-associated signatures”

    Human trialearly after reperfusionlung

    Longitudinal multi-omic profiling of a pig-to-human lung xenograft reveals phased immune and tissue-remodeling responses

    Research Square11 Aug 2026Preprint

More on Complement system

Surfactant-associated proteins

upin humans1

1 study
  1. Pig-to-human lung xenotransplantation increases surfactant-associated proteins in humans.

    “surfactant-associated proteins and epithelial-remodeling signatures increased, coinciding with partial histological improvement”

    Human triallung9 days

    Longitudinal multi-omic profiling of a pig-to-human lung xenograft reveals phased immune and tissue-remodeling responses

    Research Square11 Aug 2026Preprint

More on Surfactant-associated proteins

Pulmonary function

upin humans1

1 study
  1. Pig-to-human lung xenotransplantation improves pulmonary function in humans.

    “surfactant-associated proteins and epithelial-remodeling signatures increased, coinciding with partial histological improvement and improved pulmonary function.”

    Human triallung9 days

    Longitudinal multi-omic profiling of a pig-to-human lung xenograft reveals phased immune and tissue-remodeling responses

    Research Square11 Aug 2026Preprint

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 1Sep 2026: 0Oct 2026: 01 in 12 months