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Impaired liver-muscle lactate metabolism causes sarcopenia via lactic acidosis in skeletal muscle in mice

Science Advances

  • HIF1A
  • Hypoxia and HIF signalling
  • NAD+ metabolism
  • Lactate
  • Sarcopenia
  • Mice

The paper

Eguchi T, Hayashiji N, Tabata S et al.

Science Advances · 4 Sep 2026

doi.org/10.1126/sciadv.aeb4011PubMed 42696581

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