Spousal concordance and interdependence in depression among older adults: A cross-cultural longitudinal study in China, the United States, and England
Abstract
BACKGROUND: Late-life depression often extends to the marital partner, yet mechanisms of dyadic interdependence and their cross-cultural generalizability remain unclear. METHODS: We analyzed harmonized longitudinal data from couples in the China Health and Retirement Longitudinal Study (CHARLS; n = 3,532; 5 waves, 2011-2020), the Health and Retirement Study (HRS; n = 2,332; 8 waves, 2006-2020), and the English Longitudinal Study of Ageing (ELSA; n = 1,895; 9 waves, 2002-2018). Depressive symptoms (CES-D) and activities of daily living (ADL)/instrumental ADL (IADL) limitations were measured at every wave. Complementary actor-partner interdependence models (APIM) and random-intercept cross-lagged panel models (RI-CLPM) were applied, with multiplicity adjustment, full-information maximum likelihood (FIML), and 20-imputation triangulation. RESULTS: Within-couple correlations of depressive symptoms were positive in every cohort (r = 0.34-0.43 in CHARLS, 0.14-0.20 in HRS, 0.23-0.29 in ELSA). APIM partner effects were robust in CHARLS but sparse elsewhere. After partialling out stable between-couple similarity, RI-CLPM within-person cross-spouse associations were attenuated, reaching consistent significance under FIML and multiple imputation only in ELSA. Four-variable RI-CLPMs showed bidirectional depression-disability coupling, strongest in HRS and ELSA, with cross-spouse function-to-depression effects in Western cohorts but not in CHARLS. Sex distinguishability was not supported, and half-longitudinal mediation through ADL/IADL did not survive multiplicity correction. CONCLUSIONS: Concordance in late-life depressive symptoms replicates across three major aging cohorts; in CHARLS, it primarily reflects stable between-couple similarity, whereas modest within-person prospective coupling persists in ELSA and in the multiple-imputation HRS estimates. Bidirectional depression-disability coupling in Western cohorts is the most replicable within-person signal, supporting combined depression management and functional rehabilitation for older couples.
- Depression
- Depressive symptoms
- Disability
- Prospective spousal depressive symptoms
- Spousal depressive symptoms
- Humans
The paper
Union Hospital; Fujian Medical University
Psychological Medicine, 1 Jan 2026, Open access


