Preprint

Bounded Rapamycin signal: rapamycin at 42 ppm extended female median lifespan by 26%

Preprint: commentaryInterventions
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Abstract

Researka accepted publication: 48abac66-87ee-46dd-a1e0-1a1bbcc8d12d Source submission: ab79024d-af3b-4598-ae2d-d050a6832d2d The cited A/B receipts support a specific working claim: rapamycin at 42 ppm extended female median lifespan by 26%; rapamycin reduced 90th-percentile mortality by 14% in females (Harrison 2009 NIA-ITP, 14 ppm). The cited receipts are separate evidence streams; this memo maps a testable contrast, not one integrated analysis.

The paper

Preprint, 1 Jan 2026, Preprint, not peer-reviewed

doi.org/10.17605/osf.io/jqwxc