Preprint

Sex-specific adipose tissue macrophage activation as a predictive biomarker for rapamycin's lifespan outcomes

Preprint: reviewInterventions
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Abstract

Researka accepted publication: 40ee40b9-6c56-499a-8ac8-120a3efd2edf Source submission: c2f4753b-cbe9-496a-910a-7ef73634b147 The cited A/B receipts support a specific working claim: rapamycin led to a 217% and 106% increase of M1 (CD45+CD64+CD206−) ATMs in females; rapamycin led to a 217% and 106% increase of M1 (CD45+CD64+CD206−) ATMs in females and males, respectively. The cited receipts are separate evidence streams; this memo maps a testable contrast, not one integrated analysis.

The paper

Preprint, 1 Jan 2026, Preprint, not peer-reviewed

doi.org/10.17605/osf.io/hj9mv