Statistica Neerlandica

COVID-19 deaths exceeded excess deaths in older Dutch people

Deaths from COVID-19 reached 0.98% of the study population, compared with 0.34% excess mortality from all causes.

Paper by Owen R. McWilliams, Mark G. J. de Boer, Liesbeth C. de Wreede, Eva A. S. Koster · Leiden University Medical Center
Figure 1 from Statistica Neerlandica
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Figure 1. McWilliams et al., CC BY
Cohort study of Dutch residents aged 63 and older, two yearsPopulations

Limit: Deaths involving COVID-19 were generally assigned to it, potentially exaggerating displacement of other causes

Edited by Boris Djordjevic · AgingResearch.News

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In the older Dutch population, researchers used a new statistical model in an observational analysis of mortality during the COVID-19 pandemic’s first two years. The model estimated deaths above expected levels for different causes. Deaths from causes other than COVID-19 occurred less often than expected. This meant COVID-19 deaths exceeded the overall excess in deaths.

Infection was associated with higher short-term mortality across all causes of death, with elevated risk persisting beyond 28 days after infection. Vaccination was associated with lower COVID-19 mortality during both the early and longer-term stages of infection.

Why it matters

For older populations, distinguishing deaths attributed to COVID-19 from changes in other causes may help assess the pandemic’s overall mortality burden.

Caveats

This observational analysis cannot establish cause and effect, and its scope was older people in the Netherlands. The results suggested bias because vaccine recipients may have been healthier, although this appeared much smaller than vaccination’s association with reduced COVID-19 mortality.

From the paper

Limitation

Some vaccination data are missing as data sharing required informed consent (Statistics Netherlands (CBS), 2022).

4.2.4 Data issues and confounding

Quoted word for word from the full text on onlinelibrary.wiley.com.