BiomarkersHumans3,076 participants4 yearsCohort study

SenMayo Based Aging Signature (Sen-Age) in cancer survivors: The Health and Retirement Study (HRS)

GSA 2025 Abstract

Abstract

The SenMayo gene set identifies senescent cells, one of the hallmarks of aging, especially among those with cancer. In the HRS cohort, we constructed a SenMayo based aging signature (Sen-Age) among those without cancer (controls) and examined its association with 4-year mortality in cancer survivors.

The paper

Seshadri G, Wang S, Guan W et al.

GSA 2025 Abstract · 31 Dec 2025 · CC BY

Presented at GSA 2025

doi.org/10.1093/geroni/igaf122.2967