Dugesia japonica

1. Resveratrol decreases Agat1 in D. japonica.

   “late stem cell marker Agat1 was significantly suppressed by high-concentration RSV.”

   Model organisms50 μM

   Resveratrol targeting Smad4 via a concentration-dependent biphasic effect regulates stem cells-mediated regeneration

   Experimental and molecular pathology·14 Feb 2026

2. Resveratrol impairs blastema regeneration in D. japonica.

   “high-concentration RSV (50 μM) caused significant inhibition.”

   Model organisms50 μM

   Resveratrol targeting Smad4 via a concentration-dependent biphasic effect regulates stem cells-mediated regeneration

   Experimental and molecular pathology·14 Feb 2026

3. Resveratrol improves blastema regeneration in D. japonica.

   “low-concentration RSV (5 μM) promoted regeneration”

   Model organisms5 μM

   Resveratrol targeting Smad4 via a concentration-dependent biphasic effect regulates stem cells-mediated regeneration

   Experimental and molecular pathology·14 Feb 2026

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