InterventionsHuman trial164 participants3 yearsRandomised trialRegistered NCT03243422

Effects of hearing intervention on blood-based biomarkers of neuroinflammation and neurodegeneration: a secondary analysis of the ACHIEVE randomised controlled trial

Fig. 1. Analysis of blood-based biomarkers obtained at baseline and follow-up from ARIC participants enrolled in ACHIEVE stratified by randomisation.
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Fig. 1. Analysis of blood-based biomarkers obtained at baseline and follow-up from ARIC participants enrolled in ACHIEVE stratified by randomisation.Analysis of blood-based biomarkers obtained at baseline and follow-up from ARIC participants enrolled in ACHIEVE stratified by randomisation.Pike et al.

EClinicalMedicine

The paper

James Russell Pike, Alison Huang, Nicholas Simon Reed,
Show 110 more authorsMichelle L. Arnold, Theresa Hnath Chisolm, David Couper, Jennifer A. Deal, Sarah P. Faucette, Adele M. Goman, Rebecca F. Gottesman, Timothy M. Hughes, David S. Knopman, Christine M. Mitchell, Thomas H. Mosley, Priya Palta, James S. Pankow, Victoria A. Sanchez, Elizabeth Selvin, Kevin Sullivan, Bharat Thyagarajan, Lynne E. Wagenknecht, Frank Robert Lin, Josef Coresh, Josef Coresh, Jennifer A. Deal, Frank Robert Lin, Marilyn S. Albert, Joshua Betz, Alden Gross, Christine M. Mitchell, Clarice Myers, Jennifer A. Schrack, Richey Sharrett, Josef Coresh, Josef Coresh, James R. Pike, Nicholas S. Reed, Alison Huang, Melissa Minotti, Spencer Bolton, Laura Sherry, James S. Pankow, Sarah Aguilar, Elizabeth Anderson, Sydney Boelter, Elizabeth Penland Miller, Debbie Ng, Kristi Oeding, Sandra Potter, Katherine H. Teece, Soni Uccellini, Matthew Waggenspack, Luanne Welch, Jacqueline M. Weycker, Kerry Witherell, Kevin Sullivan, Thomas H. Mosley, Latilraka Anderson, Julia Burt, April Carr, Arkenya Carter, Sarah P. Faucette, Rachel Foster, Ceola Greenwood, Temeka Griffin, Candace Jones, Dawn S. McLendon, Thomas H. Mosley, Stacee Naylor, Jenny Newman, Deidre O'Connor, Tiffany Owens, Jeraline Sims, Allison Thweatt, Tamikia Washington, Lynne E. Wagenknecht, Kathleen M. Hayden, Bria Backman, Debbie Barr, Joshua Evans, Jaime Hampton, Hailley Humphrey-Rutledge, Kaila H. Liou, Ashely Mitchell, Susan Smith, Shelton Np, Theresa Chisolm, Victoria Sanchez, Michelle Arnold, Ann Clock Eddins, Emily Moore, Haley Neil, Preyanca H. Oree, Laura Westermann, Nancy W. Glynn, Yurun Cai, Theresa Gmelin (11782674), David Couper, Sheila Burgard, Lisa Gravens-Mueller, David Li, Adele M. Goman, Clifford R. Jack, David Knopman, Denise Reyes, Anthony J. Spychalla, Kaely B. Thostenson, Douglas R Galasko, Julie E. Buring, Judy R. Dubno, Tom Greene, Lawrence R. Lustig, Coryse St. Hillaire‐Clarke,
Matt Sutterer

New York University

EClinicalMedicine · 3 Sep 2026

doi.org/10.1016/j.eclinm.2026.104164PubMed 42733779